July 25, 2008

New Pall Membrane Separates Plasma From Whole Blood Without Centrifugation

A new specialized membrane for one-step separation of plasma from whole blood without the use of centrifugation will be introduced by Pall Life Sciences later this month at the annual meeting of the American Association for Clinical Chemistry (AACC)

Zetasizer Nano Helps Establish Size Independence In DNA Driven Nanoparticle Structuring

A research team led by Dr Oleg Gang at the Brookhaven Center for Functional Nanomaterials (CFN) in New York is using the Zetasizer Nano particle characterization system from Malvern Instruments in ground-breaking work that has demonstrated successful DNA-guided formation of ordered 3-D crystalline structures

Adult stem cells activated in mammalian brain

Adult stem cells originate in a different part of the brain than is commonly believed, and with proper stimulation they can produce new brain cells to replace those lost to disease or injury, a study by UC Irvine scientists has shown.

Researchers identify gene responsible for rare childhood disease

The chromosomal abnormality that causes a rare, but often fatal, disorder that affects infants has been identified by researchers at the University of California, San Diego School of Medicine, who happened to treat two young children with the disease in San Diego – two of perhaps a dozen children in the entire country diagnosed with the disorder.

July 24, 2008

MeV+R: using MeV as a graphical user interface for Bioconductor applications in microarray analysis

We present MeV+R, an integration of the JAVA MultiExperiment Viewer program with Bioconductor packages. This integration of MultiExperiment Viewer and R is easily extensible to other R packages and provides users with point and click access to traditionally command line driven tools written in R. We demonstrate the ability to use MultiExperiment Viewer as a graphical user interface for Bioconductor applications in microarray data analysis by incorporating three Bioconductor packages RAMA, BRIDGE and iterativeBMA.

July 23, 2008

Transcending Boundaries

From understanding climate change to predicting infectious disease outbreaks to engineering solutions to address disability, scientific research is increasingly crossing the boundaries between disciplines. Fostering interdisciplinary research, education and training as a means of developing the next generation of researchers is a key goal of the National Science Foundation's (NSF) Integrative Graduate Education Research Traineeship (IGERT) program. Through IGERT, graduate students work as part of interdisciplinary teams, learning the language of other disciplines as they collaborate to confront some of the major challenges of the day........

Measuring the stress of forested areas

Plants undergo stress because of lack of water, due to the heat or the cold or to excess of light. A research team from the University of the Basque Country have analysed the substances that are triggered in plants to protect themselves, with the goal of choosing the species that is best suited to the environment during reforestation under adverse environmental conditions........

July 22, 2008

Plastic architecture of bacterial genome revealed by comparative genomics of Photorhabdus variants

Background: The phenotypic consequences of large genomic architecture modifications inside a clonal bacterial population are rarely undertaken because of the difficulties involved in using molecular approaches on a mixed population. Bacterial variants frequently arise among the Photorhabdus luminescens species, a nematode-symbiotic and insect-pathogenic bacterium. We therefore studied genome plasticity inside Photorhabdus variants. Results: We used a combination of macrorestriction and DNA microarray experiments to perform a comparative genomic study of different Photorhabdus luminescens TT01 variants. Prolonged culturing of TT01 strain and a genomic variant, collected from the laboratory-maintained symbiotic nematode, generated bacterial lineages composed of primary and secondary phenotypic variants and colonial variants. The primary phenotypic variants express several characters that are absent from the secondary forms. We reveal substantial plasticity of the genome architecture of some variants, mediated mainly by deletions in the "flexible" gene pool of the TT01 reference genome and also by genomic amplification. We showed that the primary or secondary phenotypic variant status is independent from global genomic architecture and that the bacterial lineages are genomic lineages. We focused on two unusual genomic changes: a deletion at a new recombination hot-spot composed of long approximate repeats; a 275 kb single block-duplication belonging to a new class of genomic duplications. Conclusions: Our findings demonstrate that major genomic variations occur in Photorhabdus clonal populations. The phenotypic consequences of these genomic changes are cryptic. This study provides new insight into the field of bacterial genome architecture and further elucidates the role of clonal genomic variation in bacterial genome evolution.

July 19, 2008

What is Meiosis?

Lily Anther Microsporocytes © John C. Glase Meiosis is a two-part cell division process in organisms that sexually reproduce. Meiosis produces gametes with one half the number of chromosomes as...

July 18, 2008

Vision Screening Device Detects Diabetes

Isn't it nice to be able to accomplish multiple things at once. Just imagine going to the eye doctor for a vision screening and while you are there, you can find...

What are Taigas?

Taigas, also called boreal or coniferous forests, are forests of dense evergreen trees that extend across North America, Europe, and Asia. Boreal Forest in California.Tupper Ansel Blake...